Compile Data Set for Download or QSAR
maximum 50k data
Found 17 of ic50 data for polymerid = 49000619,50002469
TargetGlutamate receptor ionotropic, kainate 3(Rattus norvegicus)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50069111((2S,4S)-2-Amino-4-(2,2-diphenyl-ethyl)-pentanedioi...)
Affinity DataIC50:  380nMAssay Description:Binding affinity against Ionotropic glutamate receptor using [3H]- CGS-19755 displacement from rat forebrain preparationsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, kainate 3(Rattus norvegicus)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50288204((2S,3S)-3-Carboxymethyl-azetidine-2-carboxylic aci...)
Affinity DataIC50:  700nMAssay Description:Compound was tested in vitro for binding affinity against Ionotropic glutamate receptor kainate using [3H]-kainate as the radioligand.More data for this Ligand-Target Pair
In DepthDetails Article
TargetGlutamate receptor ionotropic, kainate 3(Rattus norvegicus)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50069120((2S,4S)-2-Amino-4-(3,3-diphenyl-propyl)-pentanedio...)
Affinity DataIC50:  1.16E+3nMAssay Description:Binding affinity against Ionotropic glutamate receptor using ACPD sensitive [3H]- glutamate displacement from rat forebrain preparationsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, kainate 3(Rattus norvegicus)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50069118((2S,4S)-2-Amino-4-(3-phenyl-propyl)-pentanedioic a...)
Affinity DataIC50:  1.84E+3nMAssay Description:Binding affinity against Ionotropic glutamate receptor using [3H]- CGS-19755 displacement from rat forebrain preparationsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, kainate 3(Rattus norvegicus)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50069118((2S,4S)-2-Amino-4-(3-phenyl-propyl)-pentanedioic a...)
Affinity DataIC50:  1.84E+3nMAssay Description:Binding affinity against Ionotropic glutamate receptor using ACPD sensitive [3H]- glutamate displacement from rat forebrain preparationsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, kainate 3(Homo sapiens (Human))
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50178136((S)-1-(2-amino-2-carboxyethyl)-3-(2-carboxybenzyl)...)
Affinity DataIC50:  4.00E+3nMAssay Description:Antagonist activity at recombinant GluK3 receptor (unknown origin) expressed in Xenopus oocyte assessed as inhibition of glutamate-induced current am...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, kainate 3(Rattus norvegicus)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50069120((2S,4S)-2-Amino-4-(3,3-diphenyl-propyl)-pentanedio...)
Affinity DataIC50:  1.32E+4nMAssay Description:Binding affinity against Ionotropic glutamate receptor using [3H]- CGS-19755 displacement from rat forebrain preparationsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, kainate 3(Homo sapiens (Human))
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50207594(2,3-Dihydroxy-6-nitro-benzo[f]quinoxaline-7-sulfon...)
Affinity DataIC50:  4.40E+4nMAssay Description:Displacement of [3H]kainate from human GLUK7 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, kainate 3(Homo sapiens (Human))
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50364074(CHEMBL1950805)
Affinity DataIC50:  8.13E+4nMAssay Description:Antagonist activity at human recombinant GluK3 receptor expressed in human HEK293 cells assessed as inhibition of glutamate-stimulated calcium influx...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, kainate 3(Rattus norvegicus)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50002370((R,S)-alpha-amino-3-hydroxy-5-methyl-4-isooxazole-...)
Affinity DataIC50: >1.00E+5nMAssay Description:Binding affinity of compound was determined against KA receptor, using radioligand [3H]- KAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, kainate 3(Rattus norvegicus)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50128264((R,S)-2-amino-3-(4-chloro-3-hydroxy-5-isoxazolyl)p...)
Affinity DataIC50: >1.00E+5nMAssay Description:Binding affinity of compound was determined against KA receptor,using radioligand [3H]- KAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, kainate 3(Rattus norvegicus)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50069111((2S,4S)-2-Amino-4-(2,2-diphenyl-ethyl)-pentanedioi...)
Affinity DataIC50: >1.00E+5nMAssay Description:Binding affinity against Ionotropic glutamate receptor using [3H]- CGS-19755 displacement from rat forebrain preparationsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, kainate 3(Rattus norvegicus)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50017244((R,S)-2-amino-3-(4-bromo-3-hydroxy-5-isoxazolyl)pr...)
Affinity DataIC50: >1.00E+5nMAssay Description:Binding affinity of compound was determined against KA receptor, using radioligand [3H]- KAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, kainate 3(Rattus norvegicus)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50049748((2S,4S)-2-Amino-4-(4,4-diphenyl-butyl)-pentanedioi...)
Affinity DataIC50:  1.47E+5nMAssay Description:Binding affinity against Ionotropic glutamate receptor using [3H]- CGS-19755 displacement from rat forebrain preparationsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, kainate 3(Rattus norvegicus)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50049748((2S,4S)-2-Amino-4-(4,4-diphenyl-butyl)-pentanedioi...)
Affinity DataIC50:  1.47E+5nMAssay Description:Binding affinity against Ionotropic glutamate receptor using [3H]- CGS-19755 displacement from rat forebrain preparationsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, kainate 3(Homo sapiens (Human))
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50185318((S)-1-(2-amino-2-carboxyethyl)-3-(2-carboxythiophe...)
Affinity DataIC50:  2.64E+5nMAssay Description:Displacement of [3H]kainate from human GLUK7 expressed in HEK293 cell membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor ionotropic, kainate 3(Homo sapiens (Human))
Jagiellonian University Medical College

Curated by ChEMBL
LigandPNGBDBM50178148((RS)-1-(2-amino-2-carboxyethyl)-3-(2-carboxybenzyl...)
Affinity DataIC50:  8.80E+5nMAssay Description:Displacement of [3H]kainate from human GLUK7 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed